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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITGB2
All Species:
9.09
Human Site:
Y735
Identified Species:
22.22
UniProt:
P05107
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05107
NP_000202.2
769
84782
Y735
H
L
S
D
L
R
E
Y
R
R
F
E
K
E
K
Chimpanzee
Pan troglodytes
NP_001029294
769
84800
Y735
H
L
S
D
L
R
E
Y
R
R
F
E
K
E
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P11835
771
85007
Y737
H
L
T
D
L
R
E
Y
R
R
F
E
K
E
K
Rat
Rattus norvegicus
P49134
799
88476
F764
I
I
H
D
R
R
E
F
A
K
F
E
K
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508168
799
87942
F764
I
I
H
D
R
R
E
F
A
K
F
E
K
E
K
Chicken
Gallus gallus
P07228
803
88535
F768
I
I
H
D
R
R
E
F
A
K
F
E
K
E
K
Frog
Xenopus laevis
P12606
798
88149
F763
I
I
H
D
R
R
E
F
A
K
F
E
K
E
K
Zebra Danio
Brachydanio rerio
XP_686012
768
84500
W733
Y
A
S
D
L
R
E
W
R
R
F
E
K
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P11584
846
92638
F811
T
I
H
D
R
R
E
F
A
R
F
E
K
E
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27874
809
90119
A773
L
H
D
R
S
E
Y
A
T
F
N
N
E
R
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
N.A.
N.A.
81.9
45.5
N.A.
45.6
45.8
46.3
50.4
N.A.
35.9
N.A.
37.9
N.A.
Protein Similarity:
100
99.7
N.A.
N.A.
N.A.
90
61.8
N.A.
62.3
62.3
62.9
66
N.A.
53.9
N.A.
56
N.A.
P-Site Identity:
100
100
N.A.
N.A.
N.A.
93.3
53.3
N.A.
53.3
53.3
53.3
66.6
N.A.
53.3
N.A.
0
N.A.
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
100
73.3
N.A.
73.3
73.3
73.3
93.3
N.A.
73.3
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
10
50
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
90
0
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
0
0
0
0
0
10
90
0
0
0
0
90
10
80
0
% E
% Phe:
0
0
0
0
0
0
0
50
0
10
90
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
30
10
50
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
40
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
40
0
0
90
0
70
% K
% Leu:
10
30
0
0
40
0
0
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
50
90
0
0
40
50
0
0
0
10
20
% R
% Ser:
0
0
30
0
10
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
10
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
10
30
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _